DEPARTMENT OF CHEMISTRY

Affiliations

Biomedical Engineering

Research Statement 

Optical coherence tomography, single-molecular imaging, ophthalmology, vision science, and genomics.

Selected Publications

1. Yang Zhang, Gaoxiang Wang, Peizhou Huang, Edison Sun, Junghun Kweon, Qianru Li, Ji Zhe, Leslie L. Ying, and Hao F. Zhang, “Minimizing molecular misidentification in imaging low-abundance protein interactions using spectroscopic single-molecule localization microscopy,” Analytics Chemistry, in press (2022)
2. Ian Rubinoff, Roman Kuranov, Zeinab Ghassabi, Yuanbo Wang, Lisa Beckmann, David Miller, Behnam Tayebi, Gadi Wollstein, Hiroshi Ishikawa, Joel S. Schuman, Hao F. Zhang, “High-speed balanced-detection visible-light optical coherence tomography in the human retina using subpixel spectrometer calibration,” IEEE Transactions on Medical Imaging 41, 1724-1734 (2022)
3. Ki-Hee Song, Benjamin Brenner, Wei-Hong Yeo, Junghun Kweon, Zhen Cai, Yang Zhang, Youngseop Lee, Xusan Yang, Cheng Sun and Hao F. Zhang, “Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy,” Nanophotonics 11, 1527-1535 (2022)
4. Yang Zhang, Yu Zhang, Ki-Hee Song, Wei Lin, Cheng Sun, George Schatz, and Hao F. Zhang, "Investigating single-molecule fluorescence spectral heterogeneity of rhodamines using high-throughput single-molecule spectroscopy," The Journal of Physical Chemistry Letters 12, 3914-3921 (2021)
5. Ki-Hee Song, Yang Zhang, Benjamin Brenner, Cheng Sun, and Hao F. Zhang, “Symmetrically-dispersed spectroscopic single-molecule localization microscopy,” Light: Science and Applications 9, 92 (2020)
6. Ki-Hee Song, Yang Zhang, Gaoxiang Wang, Cheng Sun, and Hao F. Zhang, “Three-dimensional biplane spectroscopic single-molecule localization microscopy,” Optica 6, 709-715 (2019)
7. Hao Li, Biqin Dong, Xian Zhang, Xiao Shu, Xiangfan Cheng, Rihan Hai, David Czaplewski, Hao F. Zhang, and Cheng Sun, “Disposable ultrasound-sensing chronic cranial window by soft nanoimprinting lithography,” Nature Communications 10, 4277 (2019)
8. Biqin Dong, Luay Almassalha, Ben E. Urban, T. Quyen Nguyen^*, Satya Khuon, Teng-Leong Chew, Vadim Backman, Cheng Sun, and Hao F. Zhang, “Super-resolution spectroscopic microscopy via photon localization,” Nature Communications 7, 12290 (2016)
9. Ji Yi, Zhen Puyang, Liang Feng, Lian Duan, Peiji Liang, Vadim Backman, Xiaorong Liu, Hao F. Zhang^§, “Optical detection of early damages in retinal ganglion cells in a mouse model of partial optic nerve crush injury,” Investigative Ophthalmology & Vision Science 57, 5665–5671 (2016)
10. Ji Yi, Wenzhong Liu, Siyu Chen, Vadim Backman, Nader Sheibani, Christine Sorenson, Amani A. Fawzi, Robert A. Linsenmeier, and Hao F. Zhang, “Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation,” Light: Science & Applications 4, e334 (2015)