Researchers Uncover Hijackable E3 Ligase for Targeted Protein degradation
July 19, 2024
Xiaoyu Zhang and members of his lab made an important discovery that sheds light on the intricate mechanisms of targeted protein degradation (TPD), an emerging path to drug discovery. Recently published in Nature Chemical Biology, this study adds to the toolkit for drug development by enabling more precise targeting of specific proteins that drive cancer and other diseases.